CSL transforms automated micro-purification with accelerated planning & data processing
Company Size
1,000+
Country
- Australia
Product
- Synthace platform
- Tecan Evo liquid-handling platform
Tech Stack
- Cloud-based experiment platform
- No-code interface
- Workflow Builder
Implementation Scale
- Departmental Deployment
Impact Metrics
- Digital Expertise
- Productivity Improvements
Technology Category
- Platform as a Service (PaaS) - Connectivity Platforms
- Platform as a Service (PaaS) - Data Management Platforms
Applicable Industries
- Healthcare & Hospitals
- Life Sciences
Applicable Functions
- Product Research & Development
- Quality Assurance
Use Cases
- Predictive Maintenance
- Process Control & Optimization
- Real-Time Location System (RTLS)
Services
- Cloud Planning, Design & Implementation Services
- Data Science Services
About The Customer
CSL is a leading global biotechnology company with a dynamic portfolio of lifesaving medicines, including those that treat hemophilia and immune deficiencies, vaccines to prevent influenza, and therapies in iron deficiency, dialysis, and nephrology. Since its beginnings in 1916, CSL has been driven by its promise to save lives using the latest technologies. Today, CSL – including its three businesses, CSL Behring, CSL Seqirus, and CSL Vifor – provides lifesaving products to patients in more than 100 countries and employs 30,000 people. CSL’s unique combination of commercial strength, R&D focus, and operational excellence enables the company to identify, develop and deliver innovations so its patients can live life to the fullest.
The Challenge
CSL set a goal of doubling the throughput of experimentation via robotics, automation & digital connectivity without a significant increase in headcount by 2030. The CSL Purification Team was looking for a solution that would enable scientists to plan and execute micro-scale purification experiments without the need to write code, ensuring their scientists could increase their throughput while improving the quality of their results. The team faced obstacles such as low uptake of automation and complicated scripting, low device utilization in lab environments, and manual management of experimental workflows & associated data. The team required a tool that would help them standardize their workflow design, execution, and data analysis processes for micro-scale purification experiments and easily transfer knowledge from one site to the next.
The Solution
The collaboration between CSL and Synthace aligned with the CSL Purification Team's goal of digital connectivity, robotics, and automation to improve process development efficiencies within the CSL Purification Team. The drag-and-drop design elements of Workflow Builder translate the CSL Purification Team's human-language directions into complex robot instructions with no custom scripting required. The in-silico simulation allows scientists to understand how their designed experiment would be physically executed on the liquid handling platform, tracking the liquids across the workflow. Synthace catches errors like impossible liquid transfers or insufficient deck space. This allows CSL Purification Team scientists to catch errors at the design stage - a great time saver, since trial runs are no longer necessary to ensure the script was set up properly ahead of the experiment. The plate reader data collected in the experiment is automatically uploaded, aligned with the liquid handling data, and analyzed by the Synthace platform without the need for manual intervention.
Operational Impact
Quantitative Benefit
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