实例探究 > Bringing a gene therapy pioneer from paper to the cloud

Bringing a gene therapy pioneer from paper to the cloud

公司规模
200-1,000
地区
  • America
  • Europe
国家
  • Netherlands
  • United States
产品
  • Benchling Notebook
  • Benchling Registry
  • Benchling Inventory
技术栈
  • Cloud Computing
  • Data Management
实施规模
  • Enterprise-wide Deployment
影响指标
  • Digital Expertise
  • Productivity Improvements
技术
  • 基础设施即服务 (IaaS) - 云计算
  • 平台即服务 (PaaS) - 数据管理平台
适用行业
  • 医疗保健和医院
  • 生命科学
适用功能
  • 产品研发
  • 质量保证
用例
  • 协作机器人
  • 预测性维护
服务
  • 云规划/设计/实施服务
  • 数据科学服务
关于客户
uniQure is a leading pioneer in the field of gene therapy. The company originated the first approved gene therapy in 2012. By leveraging their modular and validated technology platform, uniQure is rapidly advancing a pipeline of AAV-based gene therapies to treat patients with hemophilia, Huntington’s disease, and other severe genetic diseases. The company is international with worksites in Amsterdam and Lexington, Massachusetts. It employs between 250 to 1000 employees. The teams using Benchling within uniQure include Research, Analytical development, Nonclinical, Vector development, and Process development.
挑战
uniQure, a leading pioneer in gene therapy, faced several challenges in their operations. As an international company with worksites in Amsterdam and Lexington, Massachusetts, they found it challenging to share data and collaborate across research sites. Their paper-based workflows made it difficult to track results and streamline experiment execution. A lack of standardized Notebook templates led to nonstandard experimental workflows and impeded quality control. These challenges were further exacerbated by the COVID-19 pandemic, which forced some uniQure scientists to work from home.
解决方案
uniQure implemented Benchling's solutions to overcome their challenges. Benchling's Notebook, Registry, and Inventory applications were used to create a complete history of every experiment, enabling scientists to track from vectors, to tissue samples, to viral batches and experimental results. Benchling protocols standardized procedures and data entry, making it easier for scientists to analyze their experiments. The company's analytical and product development teams used Benchling to track every sample in their freezers, linking location data directly to results readouts. This digital system enabled internationally distributed researchers to collaborate and discover data much more easily, even when working from home due to the COVID-19 pandemic.
运营影响
  • End-to-end tracking for gene therapy workflows was achieved, with Benchling automatically creating a complete history of every experiment.
  • International collaboration was improved, even while working remotely, due to the digital system.
  • Efficiency was improved and enthusiastic adoption was seen, with 100% of the scientists licensed to use Benchling using the Notebook every day.
  • Benchling Templates massively improved scientist efficiency, allowing scientists to spend their time analyzing results instead of typing away at a calculator.
  • Automatic audit trails and straightforward Notebook review processes ensured regulatory compliance and cut down on the time managers spend signing off on experiments.
数量效益
  • 100% of the scientists licensed to use Benchling use the Notebook every day.

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