CRUK Cancer Therapeutics Unit at the Institute of Cancer Research – Case Study Part IV: A Dotmatics Project Environment
Company Size
200-1,000
Region
- Europe
Country
- United Kingdom
Product
- Dotmatics integrated suite
- Dotmatics Gateway
- Dotmatics Browser
- Dotmatics Studies
- Vortex data analysis suite
Tech Stack
- Web-based data management
- Data analysis and storage
Implementation Scale
- Enterprise-wide Deployment
Impact Metrics
- Digital Expertise
- Productivity Improvements
Technology Category
- Analytics & Modeling - Data-as-a-Service
- Platform as a Service (PaaS) - Data Management Platforms
Applicable Industries
- Healthcare & Hospitals
- Life Sciences
Applicable Functions
- Product Research & Development
- Quality Assurance
Services
- Data Science Services
- System Integration
About The Customer
The Cancer Research UK Cancer Therapeutics Unit (CTU) at The Institute of Cancer Research is the largest academic cancer drug discovery and development group worldwide. Since 2005, the CTU, together with its collaborators, has discovered 17 preclinical development candidates; seven of which are currently in clinical trials. The research teams that make up the CTU, and in particular the Chemistry department within the Unit, all rely heavily on the Dotmatics informatics platform. Serving as the central point of convergence for the 163 people who staff the Unit, Dotmatics Gateway is a document management solution that holds all project information and standard operating procedures. The CTU currently holds 115 seats for Browser, with levels of access that vary from full, director-level access to read-only access for specific projects.
The Challenge
The Cancer Research UK Cancer Therapeutics Unit (CTU) at The Institute of Cancer Research, the largest academic cancer drug discovery and development group worldwide, was facing a challenge in managing its drug discovery projects. There was no cheminformatics platform in place at the CTU to consolidate and provide quick and easy access to data, which had led to only certain people having full access to the project data landscape. This was limiting the ability of the team to freely access data, analyze it, see the correlations, and then being able to use those correlations to determine what direction to head in – all in real time. Moreover, it was hindering the opportunity for everyone to review the data, challenge discrepancies, spot outliers and have input into what that next step should be.
The Solution
The CTU implemented the Dotmatics integrated suite of scientific informatics solutions to manage all its drug discovery projects. The Dotmatics Gateway, a document management solution, holds all project information and standard operating procedures. All project data is managed by and accessible through Dotmatics Browser, a flexible web-based query and reporting tool that consolidates all disparate databases into one central resource. The CTU can assign a set number of seats to named collaborators within the external organisation who are then provided with a security code. This code means that only specific projects and their associated data and documentation can be accessed by the external organisation, and both the named collaborators and the assigned level of project access can be easily amended by the CTU at any time. When new assay data comes in to the CTU it is immediately uploaded via Dotmatics Studies, a web-based data management solution that enables the creation, capture, analysis and storage of scientific data.
Operational Impact
Quantitative Benefit
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