Building a Better DNA Assembly Line
Company Size
11-200
Region
- America
Country
- United States
Product
- Twist Bioscience DNA Fragments
- TeselaGen DESIGN and BUILD Software
- Labcyte Echo Liquid Handler
Tech Stack
- Cloud-based Software
- API Integration
- Silicon-based DNA Synthesis
Implementation Scale
- Enterprise-wide Deployment
Impact Metrics
- Cost Savings
- Productivity Improvements
- Waste Reduction
Technology Category
- Analytics & Modeling - Machine Learning
- Application Infrastructure & Middleware - Data Exchange & Integration
- Functional Applications - Product Lifecycle Management Systems (PLM)
Applicable Industries
- Chemicals
- Food & Beverage
- Life Sciences
Applicable Functions
- Product Research & Development
- Quality Assurance
Use Cases
- Predictive Quality Analytics
- Process Control & Optimization
- Remote Control
Services
- Cloud Planning, Design & Implementation Services
- Software Design & Engineering Services
- System Integration
About The Customer
Arzeda is a biotechnology company that designs and creates proteins for various industries, including life sciences, food, and chemicals. The company focuses on delivering important molecules by testing thousands of protein-producing plasmids. Arzeda aims to provide cost-effective and sustainable production of value-added specialty chemicals and ingredients. The company leverages computational protein design to build novel enzymes and develop new pathways, unlocking new opportunities for specialty chemicals, advanced materials, and health and nutrition products.
The Challenge
Arzeda needed a more efficient and less error-prone method to construct plasmids for producing designer proteins. The existing process was slow, resource-intensive, and prone to errors. The company faced a choice: either hire additional personnel to develop a new solution from scratch or integrate proven technologies from trusted vendors into a seamless, high-throughput DNA assembly platform.
The Solution
Arzeda opted to integrate proven technologies from trusted vendors to create a seamless, high-throughput DNA assembly platform. They combined Twist Bioscience’s high-quality DNA fragments, TeselaGen’s DNA assembly design and laboratory automation software, and Labcyte’s Echo Liquid Handler. This integrated solution increased productivity, reduced consumable use, generated more accurate plasmid designs, and lowered costs. Twist Bioscience’s silicon-based DNA synthesis platform quickly and affordably produced high-quality synthetic DNA, which Arzeda combined into plasmids using sophisticated DNA assembly methods. TeselaGen’s software automated the process of DNA assembly, determining the best way to put plasmids together and which DNA fragments should be synthesized by Twist. The Labcyte Echo Liquid Handler used sound waves to move nanoliter-sized liquid droplets, making the process more efficient and reducing costs.
Operational Impact
Quantitative Benefit
Case Study missing?
Start adding your own!
Register with your work email and create a new case study profile for your business.
Related Case Studies.
Case Study
The Kellogg Company
Kellogg keeps a close eye on its trade spend, analyzing large volumes of data and running complex simulations to predict which promotional activities will be the most effective. Kellogg needed to decrease the trade spend but its traditional relational database on premises could not keep up with the pace of demand.
Case Study
Honeywell - Tata Chemicals Improves Data Accessibility with OneWireless
Tata was facing data accessibility challenges in the cement plant control room tapping signals from remote process control areas and other distant locations, including the gas scrubber. Tata needed a wireless solution to extend its control network securely to remote locations that would also provide seamless communication with existing control applications.
Case Study
HEINEKEN Uses the Cloud to Reach 10.5 Million Consumers
For 2012 campaign, the Bond promotion, it planned to launch the campaign at the same time everywhere on the planet. That created unprecedented challenges for HEINEKEN—nowhere more so than in its technology operation. The primary digital content for the campaign was a 100-megabyte movie that had to play flawlessly for millions of viewers worldwide. After all, Bond never fails. No one was going to tolerate a technology failure that might bruise his brand.Previously, HEINEKEN had supported digital media at its outsourced datacenter. But that datacenter lacked the computing resources HEINEKEN needed, and building them—especially to support peak traffic that would total millions of simultaneous hits—would have been both time-consuming and expensive. Nor would it have provided the geographic reach that HEINEKEN needed to minimize latency worldwide.
Case Study
Advanced Elastomer Systems Upgrades Production
In order to maintain its share of the international market for thermoplastic elastomers AES recently expanded its Florida plant by adding a new production line. While the existing lines were operating satisfactorily using a PROVOX distributed control system with traditional analog I/O, AES wanted advanced technology on the new line for greater economy, efficiency, and reliability. AES officials were anxious to get this line into production to meet incoming orders, but two hurricanes slowed construction.
Case Study
Energy Management System at Sugar Industry
The company wanted to use the information from the system to claim under the renewable energy certificate scheme. The benefit to the company under the renewable energy certificates is Rs 75 million a year. To enable the above, an end-to-end solution for load monitoring, consumption monitoring, online data monitoring, automatic meter data acquisition which can be exported to SAP and other applications is required.
Case Study
Coca Cola Swaziland Conco Case Study
Coco Cola Swaziland, South Africa would like to find a solution that would enable the following results: - Reduce energy consumption by 20% in one year. - Formulate a series of strategic initiatives that would enlist the commitment of corporate management and create employee awareness while helping meet departmental targets and investing in tools that assist with energy management. - Formulate a series of tactical initiatives that would optimize energy usage on the shop floor. These would include charging forklifts and running cold rooms only during off-peak periods, running the dust extractors only during working hours and basing lights and air-conditioning on someone’s presence. - Increase visibility into the factory and other processes. - Enable limited, non-intrusive control functions for certain processes.
